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KOH Chong Lek

PhD, DIC, FASc, FMSA
Senior Lecturer
Sub-Dean, Higher Degrees by Research
67903374
chonglek.koh@nie.edu.sg
NATURAL SCIENCES & SCIENCE EDUCATION
OFFICE OF GRADUATE STUDIES AND PROFESSIONAL LEARNING
NIE7-03-118D
molecular biology, metagenomics, bioethics

CL Koh retired as a professor at the Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia, where he served for more than 34 years as tutor, lecturer, associate professor, and professor.

He joined the National Institute of Education in December 2004. He served as Head, DNA Centre@NIE, from December 2004 to June 2009. Currently, he is Sub-Dean, Higher Degrees (Research), a post he held since July 2009. He is also the Senior Hall Fellow of Hall of Residence 11, NTU.

Among the awards that he had received are the inaugural “MSMBB-Applied Biosystems Award” (2001) from the Malaysian Society for Molecular Biology and Biotechnology; the “1996 Science & Technology Award” from the Malaysia Toray Science Foundation; the 2000 MACEE Fulbright Malaysian Scholar Program Award from the Malaysian-American Commission on Educational Exchange; and the inaugural Royal Society Malaysian Fellowship in 1988/89 from the British High Commission, Malaysia. He provides human individual identification service (e.g., rape and paternity cases) based on DNA typing of both chromosomal and mitochondrial genes to the general public in Malaysia since 1993. He used DNA typing to confirm the identity of some of the victims after the collapse of the Highland Tower Condominium in Kuala Lumpur in 1993/94 and identify nine badly burnt victims of the Tawau plane crash, Sabah, in 1995. He was a member of the team that discovered that Malaysian Island flying-foxes are the natural animal reservoir of Nipah virus. The team included SK Lam and KB Chua, who discovered the Nipah virus. The team also determined the nucleotide sequences of Nipah virus isolates from humans and bats.

He has vast experience in organizing seminars, conferences, and workshops, as well as conducting training courses in molecular biology and recombinant DNA technology. He has been invited, nationally and internationally, to deliver lectures and seminars on genetics, genetic engineering, DNA, cloning, the Human Genome Project, Nipah virus, biosafety, bioethics, and other up-to-date topics to a wide range of societies, agencies, schools, colleges, universities, meetings, training courses, and audience.

Academic Background

  • BSc (Hons) University of Malaya, Malaysia
  • MSc University of Malaya, Malaysia
  • PhD University of London, UK
  • DIC Imperial College of Science & Technology, UK

Professional Organisations

  • Fellow, Academy of Sciences Malaysia (FASc)
  • Fellow, Malaysian Scientific Association (FMSA)
  • Founder Member, Asia-Pacific International Molecular Biology Network (A-IMBN)
  • Life member, Malaysian Society for Molecular Biology and Biotechnology
  • Life member, Genetics Society of Malaysia
  • Member, The Singapore Institute of Biology

Courses

  • AAB103  General Microbiology
  • AAB104  Current Genetics
  • ASK301  Topics in Biological Science for Primary Science Teaching
  • DSS100  Selected Topics for Primary Science Teaching (Biological Sciences)
  • INS0025  Laboratory Techniques in Life Science
  • INS2077  GCE O-Level Biology: Molecular Genetics, Hands-on Workshop
  • MLS871  Advanced Animal Biotechnology

Research Interests

  • Quorum sensing and quorum quenching in bacteria
  • Bioethics
  • Biosafety

Professional Activities

  • 1998 to now: Member of the Founding Governing Council of the Asia-Pacific International Molecular Biology Network
  • Member of the International Advisory Board of the 21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology ‘Biomolecules for Quality of Life’, 2-7 Aug 2009, Shanghai, China, International Union of Biochemistry and Molecular Biology (IUBMB)
  • 2004-2007: External Examiner for the Bachelor of Science (Hons) Biotechnology, Universiti Tunku Abdul Rahman, Malaysia
  • Co-chairman, Organizing Committee, 9th A-IMBN Conference and 16th MSMBB Scientific Meeting, 4-5 Sep 2006, Kuala Lumpur, Malaysia, Asia-Pacific International Molecular Biology Network and Malaysian Society for Molecular Biology and Biotechnology
  • Member of the International Advisory Board of the 20th IUBMB and 11th FAOBMB International Congress of Biochemistry and Molecular Biology ‘Life: Molecular Integration & Biological Diversity’, 18-23 Jun 2006, Kyoto, Japan, International Union of Biochemistry and Molecular Biology (IUBMB)
  • 1994 to 2004: The Malaysian Representative of the National Point of Contact (NPCR) of the UNESCO Regional Network for Microbiology and Microbial Biotechnology in Southeast Asia
  • The Malaysian Government Representative to the Third Session of the Intergovernmental Bioethics Committee (IGBC) on 23-24 June 2003 at UNESCO House in Paris, France
  • 1995 to 2004: Member of the National Genetic Manipulation Advisory Committee, Ministry of Science, Technology and the Environment, Malaysia
  • 2004: Member of the Malaysian delegate to the 7th Meeting of the Conference of Parties and the 1st Meeting of the Parties (MOP1) to the protocol on biosafety of the Convention on Biological Diversity (CBD), Kuala Lumpur, Malaysia
  • 1999 to 2000, 2002 to 2008: Chairman, Dr. Ranjit Bhagwan Singh Memorial Lecture Organising Committee (Academy of Sciences Malaysia)
  • Chairman of the International Organizing Committee of the 7th Asian Conference on Transcription (ACT-VII), 23–27 July 2002, Kuala Lumpur, Malaysia
  • 1996 to 2001: Executive Secretary, UNESCO Regional Network for Microbiology and Microbial Biotechnology in Southeast Asia
  • 1993 to 1997: President of the Malaysian Society for Molecular Biology and Biotechnology
  • 1993 to 1998: Co-Editor, Asia-Pacific Journal of Molecular Biology and Biotechnology

Graduate Supervision

  • Completed — 11 PhD and 34 Masters (at the University of Malaya)

BOOKS

Koh, C.L. (1990). Recombinant DNA Techniques. A Laboratory Manual for the Training Course (PP. 91). Kuala Lumpur: University of Malaya.

CONFERENCE PAPERS PUBLISHED IN PROCEEDINGS

Koh, C.L., Lian, L.H., & Lim, M.E. (2001, November). Casework: Using the hypervariable regions of human mitochondrial DNA to determine familial relationship in Malaysia. IN na (ED.) Towards Commercialization of Malaysian Biotechnology (13th National Biotechnology Seminar), na, 347-349.
Koh, C.L., Nakatome, M., Honda, K., Tun, Z., Lim, M.E., Sam, C.K., & Wakasugi, C. (1997, July). Genetic polymorphism in the 3' flanking untranslated region of the human dopamine transporter gene (DAT1) in 105 Chinese in Malaysia. IN C. Wakasugi (ED.) Advances in Legal Medicine 3: The 3rd International Symposium of Advances In Legal Medicine (ISALM) [September 1996], na, 215-219.
Honda K., Nakatome M., Tun Z., Sakurada M., Koh C.L., Lim M.E., Misawa, S., & Wakasugi C. (1997, August). A variation map based on nucleotide sequences of mt-DNA control regions of Asian populations. IN ISFH Hakone Symposium Program Committee (ED.) ISFH Hakone Symposium on DNA Polymorphisms 1996: Advances in Research on DNA Polymorphisms, na, 180-183.
Koh, C.L., Lim, M.E., & Jeffreys, A.J. (1994, November). HgaI site variation in the DNA flanking the hypervariable minisatellite MS31 (locus D7S21) in the Malaysian population. IN Koh, C.L. (ED.) Proceedings of the First National Congress on Genetics, na, 234-236.
Koh, C.L. (1994, November). Prospects of genetics and biotechnology in Malaysia (Keynote Lecture). IN Koh, C.L. (ED.) Proceedings of the First National Congress on Genetics, na, 7-20.
Koh, C.L., Leong, K.H., Kaladevi, R., Amir, F.M., & Lim, M.E. (1992, August). Direct cloning of transcriptional promoters functioning in Escherichia coli from cryptic plasmids of Thermus species. IN Geirsdottir, A.M., Brown, H.P., & Skjenstad, T. (EDS.) Thermophiles: Science and Technology, na, 95.
Koh C.L. (1989, December). Genetics, molecular biology, and biotechnology of thermophilic bacteria. I. Construction of a genomic library of an extreme thermophile. IN Z.C. Alang (ED.) Proceedings of the First Seminar on National Biotechnology Programmes, na, 79.
Koh, C.L. (1984, June). Mutations affecting the transport of basic amino acids in Neurospora crassa. IN Othman, I., & Lim, S.T. (EDS.) Proceedings of the 10th Annual Conference of the Malaysian Biochemical Society, na, 1-6.

CONFERENCE PAPERS WITHOUT PROCEEDINGS

Koh, C. L., Sam, C. K., & Chan, K. G. (2012, March). The pitcher fluids of Nepenthes species are a rich source of microbial diversity (Invited Lecture). PAPER PRESENTED AT 14th Asia-Pacific International Molecular Biology Network (A-IMBN) Annual Conference: Life Science and Frontiers of Biorefinery Technology, Bangkok.
Koh, C.L., & Sam, C.K. (2011, February). Updating pedagogical content knowledge of teachers in molecular biology - Singapore's experience (Invited Lecture). PAPER PRESENTED AT 6th Asian-Pacific Organization for Cell Biology Congress ("Challenges in Cell Biology: Health, Agriculture, Industry and Education"), Manila.
Koh, C.L. (2010, July). Updating technological pedagogical content knowledge of teachers - Singapore's experience (Invited Lecture). PAPER PRESENTED AT 2nd Science & Mathematics Education Workshop for Stakeholders 2010, Kota Kinabalu, Sabah.
Siti Nur Aishah, A.H., Sam, C.K., & Koh, C.L. (2009, June). Investigating bacteria in the pitcher fluids of Nepenthes ventrata by culture-dependent and -independent approaches. PAPER PRESENTED AT BAGECO 10 Bacterial Genetics and Ecology - Coexisting on a Changing Planet, Uppsala.
Koh, C.L., Lee, P.P.F., Sam, C.K., & Tan, T.T.M (2008, July). Inculcating an interest in DNA science among school teachers in Singapore. PAPER PRESENTED AT XX International Congress of Genetics: "Genetics - Understanding Living Systems", Berlin.
Koh, C.L., & Chan, K.G. (2007, August). Metagenomics: Discovering microbial diversity (Invited Lecture). PAPER PRESENTED AT 24th World Congress of Pathology and Laboratory Medicine, Subang Jaya.
Koh, C.L. (2007, August). The role of molecular methods in crime scene investigation (Invited Lecture). PAPER PRESENTED AT 24th World Congress of Pathology and Laboratory Medicine, Subang Jaya.
Chan, K.G., & Koh, C.L. (2007, August). Metagenomics: Mining novel genes (Invited Lecture). PAPER PRESENTED AT 24th World Congress of Pathology and Laboratory Medicine, Subang Jaya.
Koh, C.L. (2005, December). Demystifying the human genome, bioethics and human rights (Invited Lecture). PAPER PRESENTED AT 12th Session of the International Bioethics Committee of UNESCO (IBC), Tokyo.
Koh, C.L. (2005, April). Educating teachers, students, and the public about issues in biotechnology (Invited Lecture). PAPER PRESENTED AT 15th Scientific Meeting of the Malaysian Society for Molecular Biology and Biotechnology, Kuala Lumpur.
Koh, C.L. (2003, December). Quorum sensing and quorum quenching in bacteria (Invited Lecture). PAPER PRESENTED AT UMS Biotechnology Symposium II - Signal transduction: Mechanisms and Applications, Kota Kinabalu, Sabah.
Koh, C.L. (2003, September). Country Report on Bioethics: Malaysia (Invited Lecture). PAPER PRESENTED AT Kyoto Conference on Dialogue and Promotion of Bioethics in Asia, Kyoto.
Koh, C.L. (2003, September). Human genomic research (Invited Lecture). PAPER PRESENTED AT Kyoto Conference on Dialogue and Promotion of Bioethics in Asia, Kyoto.
Koh, C.L. (2002, June). Conservation and sustainable use of biodiversity through biotechnology (Invited Lecture). PAPER PRESENTED AT Symposium on the Exclusive Economic Zone: The impact of the EEZ in the Asia Pacific - Is it promoting sustainable development or provoking conflict?, Bali.
Koh, C.L. (2002, February). Developments relating to reproductive human cloning at international and national levels (Invited Lecture). PAPER PRESENTED AT Seminar on Reproductive Human Cloning, Ministry of Foreign Affairs, Malaysia, and ISIS Malaysia, Kuala Lumpur.
Koh, C.L. (2002, October). Genetic databases of the Malaysian population (Invited Lecture). PAPER PRESENTED AT Special Seminar & National Launch of WHO Report on "WHO Genomics and World Health", Academy of Sciences Malaysia, Ministry of Health, Malaysia, and World Health Organization, Kuala Lumpur.
Koh, C.L. (2002, October). Country Report on Bioethics: Malaysia (Invited Lecture). PAPER PRESENTED AT Dialogue and Promotion of Bioethics in Asia: The Manila Conference on Bioethics, Manila.
Koh, C.L., Wong, H.L., Lim, M.E., & Sam, C.K. (2001, May). Antibiotic resistance transposons from Salmonella typhi. PAPER PRESENTED AT 101st General Meeting, American Society for Microbiology, Orlando, Florida.
Koh, C.L. (2001, September). The Human Genome Project (Invited Lecture). PAPER PRESENTED AT International Conference on Public Understanding of Science and Technology 2001 - Communicating Science to the Public (PUSAT 2001 - CSP), Kota Kinabalu, Sabah.
Koh, C.L. (1998, October). Molecular diagnosis and individual identification in Malaysia (Invited Lecture). PAPER PRESENTED AT International Symposium "Biotechnology in Tropics": 20 Years International Collaboration and the Perspectives for 21st Century, Osaka.
Koh, C.L., & Jeffreys, A.J. (1993, May). Digital DNA typing (Invited Lecture). PAPER PRESENTED AT Sixth National Molecular Biology Lecture and Fourth Scientific Meeting of the Malaysian Society for Molecular and Cellular Biology, Genting Highlands.
Koh, C.L. (1992, November). The polymerase chain reaction: its principles and applications in forensic biology (Guest Lecture). PAPER PRESENTED AT LEGALMEDSI 92: The 4th Indo-Pacific Congress on Legal Medicine and Forensic Sciences, Bangkok.
Koh, C.L. (1991, December). Promoter Probing: A Reverse Genetic Method for Analysis of Cryptic Genomes (Guest Lecture). PAPER PRESENTED AT Fourth National Molecular Biology Seminar and Second Scientific Meeting of the Malaysian Society for Molecular and Cellular Biology, Serdang.
Samuel, S., Koh, C.L., Pang, T., & Lam, S.K., (1990, August). Nucleotide and deduced amino acid sequences of genes encoding the structural proteins of three dengue-2 viruses, M1, M2 and M3, isolated in Malaysia from patients with dengue haemorrhagic fever, dengue shock syndrome and dengue fever, respectively. PAPER PRESENTED AT VIIIth International Congress of Virology, Berlin.
Koh, C.L. (1989, October). Molecular biology for the physician (Guest Lecture). PAPER PRESENTED AT 23rd Malaysia-Singapore Congress of Medicine with the participation of the Royal College of Surgeons of England, Kuala Lumpur.
Samuel, S., Koh, C.L., Blok, J., Lam, S.K., & Pang, T (1989, February). Molecular analysis of Malaysian dengue-2 viruses. PAPER PRESENTED AT Proceedings of the 25th Annual Scientific Seminar of the Malaysian Society of Parasitology and Tropical Medicine, Kuala Lumpur.
Koh, C.L. (1985, October). Plant genetic engineering - A prospectus (Guest Lecture). PAPER PRESENTED AT 2nd National Plant Tissue Culture Symposium and the International Rubber Tissue Culture Workshop, Serdang.

JOURNAL ARTICLES

Yin, W. F., Tung, H. J., Sam, C. K., Koh, C.L., & Chan, K. G. (2012). Quorum quenching Bacillus sonorensis isolated from soya sauce fermentation brine (doi:10.3390/s120404065). Sensors, 12,(4), 4065-4073.
Hong, K. W., Koh, C. L., Sam, C. K., Yin, W. F., & Chan, K. G. (2012). Quorum quenching revisited — From signal decays to signalling confusion (doi:10.3390/s120404661). Sensors, 12,(4), 4661-4696.
Wong, C. S., Yin, W. F., Sam, C.K., Koh, C. L., & Chan, K. G. (2012). Characterisation of wetland quorum quenching Pseudomonas aeruginosa strain 2SW8 and its 2-heptyl-3-hydroxy-4-quinolone production. New Microbiologica, 35,(1), 43-51.
Chong, T. M., Koh, C. L., Sam, C. K., Choo, Y. M., Yin, W. F., & Chan, K. G. (2012). Characterization of quorum sensing and quorum quenching soil bacteria isolated from Malaysian tropical montane forest (doi:10.3390/s120404846). Sensors, 12,(4), 4846-4859.
Wong, C. S., Yin, W. F., Choo, Y. M., Sam, C.K., Koh, C.L., & Chan, K.G. (2012). Coexistence of quorum-quenching and quorum-sensing in tropical marine Pseudomonas aeruginosa strain MW3A (doi:10.1007/s11274-011-0836-x). World Journal of Microbiology and Biotechnology, 28,(2), 453-461.
Yin, W. F., Purmal, K., Chin, Y. S., Chan, X. Y., Koh, C.L., Sam, C.K., & Chan, K.G. (2012). N-acyl homoserine lactone production by Klebsiella pneumoniae isolated from human tongue surface (doi:10.3390/s120303472). Sensors, 12,(3), 3472-3483.
Sautter, R., Ramos, D., Schneper, L., Ciofu, O., Wassermann, T., Koh, C. L., Heydorn, A., Hentzer, M., Høiby, N., Kharazmi, A., Molin, S., DeVries, C. A., Ohman, D. E., & Mathee, K. (2012). A complex multilevel attack on Pseudomonas aeruginosa algT/U expression and AlgT/U activity results in the loss of alginate production (dx.doi.org/10.1016/j.gene.2011.11.005). Gene, 498,(2), 242-253.
Chong, Y. M., Yin, W. F., Ho, C. Y., Mustafa, M. R., A. Hadi, A. H., Awang, K., Narrima, P., Koh, C. L., Appleton, D. R., & Chan, K. G. (2011). Malabaricone C from Myristica cinnamomea exhibits anti-quorum sensing activity (DOI: 10.1021/np100872k). Journal of Natural Products, 74,(10), 2261-2264.
Chan, K. G., Atkinson, S., Mathee, K., Sam, C. K., Chhabra, S. R., Cámara, M., Koh, C. L., & Williams, P. (2011). Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: Co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia (A-IMBN Research Highlights, http://www.natureasia.com/A-IMBN/article.php?id=486). BMC Microbiology, 11:51,(), doi:10.1186/1471-2180-11-51.
Chan, K. G., Wong, C. S., Yin, W. F., Sam, C. K., & Koh, C. L. (2010). Rapid degradation of N-3-oxo-acylhomoserine lactones by a Bacillus cereus isolate from Malaysian rainforest soil (DOI 10.1007/s10482-010-9438-0). Antonie van Leeuwenhoek, 98,(3), 299-305.
Maha, A., Gan, G. G., & Koh, C. L. (2010). Phenotype and TCR-gamma gene rearrangements in a Malaysian cohort of T-cell leukaemia/lymphoma cases. Hematology, 15,(6), 382-390.
Chan, K.G., Yin, W.F., Sam, C.K., & Koh, C.L. (2009). A novel medium for the isolation of N-acylhomoserine lactone-degrading bacteria (DOI 10.1007/s10295-008-0491-x). Journal of Industrial Microbiology & Biotechnology, 36,(2), 247-251.
Lian, L.H., & Koh, C.L. (2006). Genetic polymorphisms of two Y chromosome markers (DYS287 and DYS385) in a Kadazan-Dusun population sample from East Malaysia. Malaysian Applied Biology, 35,(1), 37-42.
Ng, K.K.S., Lee, S.L., Saw, L.G., Plotkin, J.B., & Koh, C.L. (2006). Spatial structure and genetic diversity of three tropical tree species with different habitat preferences within a natural forest. Tree Genetics & Genomes, 2,(3), 121-131.
Lian, L.H., & Koh, C.L. (2005). Genetic polymorphisms in mitochondrial DNA hypervariable regions I, II and III of the Malaysian population. Asia Pacific Journal of Molecular Biology & Biotechnology, 13,(2), 79-85.
Kong, K. F., Jayawardena, S. R., Indulkar, S. D., del Puerto, A., Koh, C. L., Hoiby, N., & Mathee, K. (2005). Pseudomonas aeruginosa AmpR is a global transcriptional factor that regulates expression of AmpC and PoxB beta-lactamases, proteases, quorum sensing, and other virulence factors. Antimicrobial Agents and Chemotherapy, 49,(11), 4567-4575.
Cha, P.C., Yamada, R., Sekine, A., Nakamura, Y., & Koh, C.L. (2004). Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations. Journal of Human Genetics, 49,(10), 558-572.
Ng, K.K.S., Lee, S.L., & Koh, C.L. (2004). Spatial structure and genetic diversity of two tropical tree species with contrasting breeding systems and different ploidy levels. Molecular Ecology, 13,(3), 657-669.
Chan Y.P., Koh C.L., Lam S.K., & Wang L.F. (2004). Mapping of domains responsible for nucleocapsid protein-phosphoprotein interaction of henipaviruses. Journal of General Virology, 85,(), 1675-1684.
Chua, K.B., Koh, C.L., Hooi, P.S., Wee, K.F., Khong, J.H., Chua, B.H., Chan, Y.P., Lim, M.E., & Lam, S.K. (2002). Isolation of Nipah virus from Malaysian Island flying-foxes. Microbes and Infection, 4,(2), 145-151.
Chan, Y.P., Chua, K.B., Koh, C.L., Lim, M.E., & Lam, S.K. (2001). Complete nucleotide sequences of Nipah virus isolates from Malaysia. Journal of General Virology, 82,(9), 2151-2155.
Yong, S., Yusuf, R., Koh, C.L., Cheah, S.C., & Ooi, L.C.L. (1999). Partial nucleotide sequence of an oleosin cDNA from Elaeis guineensis Jacq.. Journal of Oil Palm Research, Special Issue,(), 18-23.
Fong, M.Y., Koh, C.L., & Lam, S.K. (1998). Molecular epidemiology of Malaysian dengue 2 viruses isolated over twenty-five years (1968-1993). Research in Virology, 149,(6), 457-464.
Koh, C.L., Lim, M.E., Ng, H.S., & Sam, C.K. (1997). D1S80 (pMCT118) allele frequencies in a Malay population sample from Malaysia. International Journal of Legal Medicine, 110,(1), 39-40.
Koh, C.L. (1996). DNA fingerprinting, profiling and typing. Isu-isu Semasa Sains dan Teknologi 1996, Malaysian Scientific Association, na,(), 1-22.
Koh, C.L., & Benjamin, D.G. (1994). HLA-DQ alpha genotype and allele frequencies in Malays, Chinese, and Indians in the Malaysian population. Human Heredity, 44,(3), 150-155.
Cheong, K.F., Koh, C.L., & Chew N.P (1994). Isolation and restriction analysis of chloroplast DNA from Hevea. Journal of Natural Rubber Research, 9,(4), 278-288.
Cao, H.H., Mukherjee, T.K., & Koh, C.L. (1994). A study of restriction fragment length polymorphisms on some sheep breeds. Acta Veterinaria et Zootechnica Sinica, 25,(5), 406-411.
Fong, M.Y., Koh, C.L., Samuel, S., Pang, T., & Lam, S.K. (1994). Nucleotide and encoded amino acid sequences of the nonstructural protein NS1 genes of three Malaysian dengue 2 viruses. Asia-Pacific Journal of Molecular Biology and Biotechnology, 2,(4), 361-367.
Cheong, K.F., & Koh C.L. (1993). Cloning and nucleotide sequence of the large subunit D-ribulose-1,5-bisphosphate carboxylase gene, rbcL, of Hevea brasiliensis. Journal of Natural Rubber Research, 8,(2), 146-153.
Chin, I.Y.M., Koh, C.L., & Bosco, J.J. (1992). ras gene mutations in Malaysian leukemia patients. Acta Haematologica, 87,(1-2), 107-108.
Prehaud, C., Harris, R.D., Fulop, V., Koh, C.L., Wong, J., Flamand, A., & Bishop, D.H.L. (1990). Expression, characterization, and purification of a phosphorylated rabies nucleoprotein synthesized in insect cells by baculovirus vectors. Virology, 178,(2), 486-497.
Fong, M.Y., Koh, C.L., Samuel, S., Pang, T., & Lam, S.K. (1990). Nucleotide sequences of the nonstructural protein NS1 gene of three dengue-2 viruses, M1, M2 and M3, isolated in Malaysia from patients with dengue haemorrhagic fever, dengue shock syndrome and dengue fever, respectively. Nucleic Acids Research, 18,(6), 1642.
Koh, C.L. (1986). Antibiotic resistance and conjugative R plasmids in clinical isolates of Enterobacteriaceae in Peninsular Malaysia. Transactions of the Royal Society of Tropical Medicine and Hygiene, 80,(1), 158-161.
Kalaimathee, K.K., Koh, C.L., & Ngeow, Y.F. (1985). Plasmid profiles of Neisseria gonorrhoeae in Peninsular Malaysia. Microbiology and Immunology, 29,(10), 921-926.
Koh, C.L., Lim, M.E., & Wong, Y.H. (1983). Plasmid-mediated transferable chloramphenicol and tetracycline resistance in Salmonella typhi (Vi phage type 25) isolated in Peninsular Malaysia. Medical Journal of Malaysia, 38,(4), 320-324.
Koh, C.L., & Ho, C.C. (1972). Mutations affecting the utilization of basic amino acids in Neurospora. Genetics, 71,(), s31-s32.

KEYNOTE ADDRESSES

Koh, C.L. (2009, August). 18th Scientific Meeting of the Malaysian Society for Molecular Biology and Biotechnology "Reflecting 25 Years of Molecular Biology and Biotechnology in Malaysia: From Small Steps to Giant Leap". KEYNOTE ADDRESS, The impact of molecular biology and biotechnology research in medicine and allied health sciences (Presidential Address II), Shah Alam, Malaysia.
Koh, C.L. (2007, May). 7th National Congress on Genetics, 'Unravelling the Secrets of the DNA'. KEYNOTE ADDRESS, Forensic DNA typing: History and trend (Plenary 6), Kota Bahru, Kelantan, Malaysia.
Koh, C.L. (2006, June). 7th Annual Scientific Meeting of the College of Pathologists, Academy of Medicine Malaysia. KEYNOTE ADDRESS, Forensic DNA typing: History and trend (The K Prathap Memorial Lecture), Kuantan, Malaysia.
Koh C.L. (2002, March). Breaching New Frontiers in Haematology, The 4th Malaysian National Haematology Scientific Meeting, Malaysian Society of Haematology. KEYNOTE ADDRESS, The human genome: present and future implications in diagnosis, prognosis, and treatment (Plenary Lecture), Penang, Malaysia.
Koh C.L. (1999, May). 3rd UNESCO National Workshop on Promotion of Microbiology in Malaysia. KEYNOTE ADDRESS, Opportunities in Microbiology and Microbial Biotechnology in Malaysia (Plenary Lecture), Bangi, Malaysia.
Koh C.L. (1996, June). Commonwealth Dental Association and Malaysian Dental Association Scientific Congress: Quality Oral Health Into The New Millennium. KEYNOTE ADDRESS, Using DNA for individual identification: DNA fingerprinting, profiling, and typing (Plenary Lecture), Kuala Lumpur, Malaysia.
Koh C.L. (1992, September). 17th Annual Conference of the Malaysian Biochemical Society. KEYNOTE ADDRESS, Recombinant DNA technology in teaching and research: A personal experience (Plenary Lecture), Bangi, Malaysia.